Composition
Each ml contains:
Fresh organic Valerian root (Valeriana officinalis) tincture (f) 1:10
Alcohol content: 56% v/v
1 ml = 36 drops
Dosage
Adults:
take 30-60 drops in a small amount of water, at bedtime. Salivate before
swallowing.
Smaller dosages (15-20 drops, a few times daily, as needed) may be used
during the day to relieve anxiety and nervousness.
Historical overview
Valerian has been used since time immemorial for all kinds of nervous
conditions. According to some authors, its name comes from the Latin «
valere » which means « to feel good, to be healthy ».
During the Middle Ages and the Antiquity, Valerian was considered as a
panacea. It was used to treat anxiety, nervousness, insomnia, hysteria,
depression, headaches, cramps, asthma, coughs, etc. During the reign of
the Sun King Louis XIV, Valerian was even considered as a perfume! More
recently, only its sedative, antispasmodic and hypnotic uses are accepted.
Most people suffer, at one time or another, of nervous problems and/or
insomnia. To the stress of modern life, add the reduction of sleeping
time (an average of one hour less per night than our ancestors of a hundred
years ago) and insomnia and nervous problems reach epidemic heights. Sleeping
pills and tranquilizers are widespread but their effects on vigilance
and mental acuity discourage their use (and for a very good reason).
Actions and pharmacology
Valerian is probably the most known of all calming herbs. It contains
many active molecules including valepotriates, sesquiterpenes and a volatile
oil containing bornyl derivatives. GABA and some GABA receptor lignans
have also been identified.(2) Many studies reached the conclusion that
the whole Valerian extract is more effective than any of its individual
parts.
Known as a sedative and hypnotic, Valerian is effective against occasional
insomnia and anxiety. It is also used for its antispasmodic(1) effect
and as supportive therapy for depression.
Valerian’s active ingredients are still the object of debates. In
vivo, valepotriates reduce benzodiazepine weaning, link with GABA receptors,
etc. Yet, valepotriates are very unstable and degrade under heat and in
acid (like the stomach) or alkaline environments. It is however possible
that they might act as pro-medications: their degradation products, baldrinal
and homobaldrinal, might have some therapeutic effects.
Sesquiterpenes like valerinic acid and kessylglycol have demonstrated
a sedative in vivo activity. Moreover, they increase GABA levels, a neurotransmitter
with a calming effect on the nervous system.
Whatever its active ingredients, Valerian’s effects on nervousness,
anxiety, insomnia and as an antispasmodic have now been proven.
The German Commission E acknowledges its benefits in cases of: restlessness,
sleeping disorders based on nervous conditions.
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